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Physical & Chemical properties

Vapour pressure

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vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
10-04-2010 / 03-11-2010
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
according to guideline
OECD Guideline 104 (Vapour Pressure Curve)
according to guideline
EU Method A.4 (Vapour Pressure)
GLP compliance:
Type of method:
effusion method: Knudsen cell
Specific details on test material used for the study:
Test item:
Identification: LCA10002
Identification of the flask: Palmitoyl proline
Batch: 1005700024
Expiry date: Not provided
Supplier: SEPPIC
Appearance: White solid block
Packaging: Plastic flask with red stopper
Quantity received: 1 kg
Date of the receipt: 11 March 2010
Storage: In darkness at room temperature
Identification number of the test item: 10-044
ca. 25 °C
Vapour pressure:
ca. 0 Pa


The mass of sample weighed was 10.42 mg. The sample was placed in a Knudsen effusion cell with an aperture size of A = 280 micrometer. Then, the cell was placed in the apparatus.

Temperature steps at 81, 85 and then 96°C were made. After the test, a clear yellow limpid liquid was observed in the cell.

Vapour pressure results

The vapour pressure of the test item was calculated by the "Knudsen software". The calculation results are summarized in the following table.

Test temperature

t (°C)

Test temperature

T (K) 

1/T (K-1)   Experimental vapour pressure P (Pa)  Log P (Pa)  Knudsen effusion cell size (micrometer)
 81 354.15   2.82E-3 6.3871E-3   -2.195  280
 85 385.15   2.79E-3  8.8970E-3  -2.051  280
 96  369.15  2.71E-3  2.2782E-2  -1.642  280
The vapour pressure of LCA10002 extrapolated at 25°C is 1.7E-5 Pa.
Executive summary:

The vapour pressure of LCA10002 extrapolated at 25°C is 1.7E-5 Pa.

Description of key information

The vapour pressure of LCA10002 extrapolated at 25°C is 1.7E-5 Pa.

Key value for chemical safety assessment

Vapour pressure:
0 Pa
at the temperature of:
25 °C

Additional information