Registration Dossier
Registration Dossier
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EC number: 807-619-2 | CAS number: 65535-29-7
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1996
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient)
- GLP compliance:
- no
- Remarks:
- Draft report
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- 4.34
- Temp.:
- 25 °C
- Remarks on result:
- other: 95 % confidence limits (4.17-4.51)
- Conclusions:
- A partition coefficient (log Pow) of 4.34 at 25 °C was determined for Epoxid-Valerat.
- Executive summary:
The n-octanol/water partition coefficient of Epoxid-Valerat was determined with the HPLC method according to OECD guideline to be Log Pow = 4.34 at 25 °C. This method is based on the correlation of the reversed phase retention data of the test compound with those of reference compounds with known log Pow values.
Reference
The log Pow value of the test compound was calculated from its log k' and the calibration line to be (at 25 °C):
| Compound | retention times [min] 1. | retention times [min] 2./3. | mean | log k' | Log Pow |
| Epoxid-Valerat | 7.03 | 7.03 | 7.03 | 0.81 | 4.34 |
Description of key information
A partition coefficient (log Pow) of 4.34 at 25°C was determined for Epoxid-Valerat.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 4.34
- at the temperature of:
- 25 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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