4-benzoylbenzene-1,2,3-triyl tris(6-diazo-5,6-dihydro-5-oxonaphthalene-1-sulphonate)

Particle size distribution (Granulometry)

Link to relevant study record(s)

Reference

Endpoint:

particle size distribution (granulometry)

Type of information:

experimental study

Adequacy of study:

key study

Study period:

14 Aug 2015

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions)

Qualifier:

according to guideline

Guideline:

other: CIPAC MT 187: Particle Size Analysis by Laser Diffraction

GLP compliance:

no

Type of method:

Laser scattering/diffraction

Type of particle tested:

primary particle

Type of distribution:

mass based distribution

Specific details on test material used for the study:

Storage conditions: Ambient temperature (10 to 30 °C), protected from light

Percentile:

D10

Mean:

2.05 µm

St. dev.:

0.15

Remarks on result:

other: Individual results: 2.15 and 1.94 µm

Percentile:

D50

Mean:

7.61 µm

St. dev.:

0.42

Remarks on result:

other: Individual results: 7.91 and 7.31 µm

Percentile:

D90

Mean:

30.1 µm

St. dev.:

1.34

Remarks on result:

other: Individual results. 31.0 and 29.1 µm

The test item consisted of mostly fine particles. The test item was tested as a liquid dispersion in n-heptane. Before the measurement the test item was mixed with n-heptane and homogenised. This homogenised dispersion was fed to the sample unit, which was filled with n-heptane. Subsequently the diluted dispersion was pumped back into the small volume sample dispersion unit.

The background was measured (n-heptane), the laser and the correct particle concentration were adjusted and then the measurement was initiated. The control software automatically does 3 measurements and takes the average as a result. Two test series of 3 measurements each were done, measurement time was 12 s.

Median values were calculated from unrounded values.

The median particle size L₅₀(D (v, 0.5): 50% of particle volume or particle mass with lower particle diameter) deduced from these distributions were:
1^st test series L₅₀= 7.91 µm; 2^nd test series L₅₀= 7.31 µm
The average of the median particle size: L₅₀= 7.61 µm

 

The particle size L₁₀(D (v, 0.1): 105 of particle volume or particle mass with lower particle diameter) deduced from these distributions were:
1^st test series: L₁₀= 2.15 µm; 2^nd test series: L₁₀= 1.94 µm
The average of the particle size: L₁₀= 2.05 µm

 

The particle size L₉₀(D (v, 0.9): 90% of particle volume or particle mass with lower particle diameter) deduced from these distributions were:
1^st test series: L₉₀= 31.0 µm; 2^nd test series: L₉₀= 29.1 µm
The average of the particle size: L₉₀= 30.1 µm

 

The particle size distribution showed a polymodal distribution. The first maximum was seen at ca. 0.8 µm and the second one at ca. 7 µm. Two shoulders at ca. 40 µm and 200 µm.

Conclusions:

The median particle size L50 of the test item deduced from the particle size distributions was 7.61 μm

Executive summary:

The determination of the particle size distribution by laser diffraction of the test item was performed according to the OECD Guideline 110 by laser diffraction. The median particle size L₅₀ of the test item deduced from the particle size distributions was 7.61 μm.

Description of key information

The determination of the particle size distribution by laser diffraction of the test item was performed according to the OECD Guideline 110. The median particle size L₅₀ of the test item deduced from the particle size distributions was 5.7 μm.