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Physical & Chemical properties

Stability in organic solvents and identity of relevant degradation products

Administrative data

Endpoint:
stability in organic solvents and identity of relevant degradation products
Type of information:
experimental study
Adequacy of study:
key study
Study period:
3-14 August 2009
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Valid method but limited documentation

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2009
Report date:
2009

Materials and methods

Principles of method if other than guideline:
Determination of stability by UV-vis-spectrometry

Test material

Constituent 1
Chemical structure
Reference substance name:
Butanamide, 2,2'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[3-oxo-, N,N'-bis(phenyl and o-tolyl) derivs.
EC Number:
272-732-0
EC Name:
Butanamide, 2,2'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[3-oxo-, N,N'-bis(phenyl and o-tolyl) derivs.
Cas Number:
68910-13-4
Molecular formula:
C32H26O4N6Cl2 - C34H30O4N6Cl2
IUPAC Name:
Reaction mass of 2,2'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'-diyl)bis(2,1-diazendiyl)]bis[3-oxo-N-phenylbutyramide], 2,2'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'-diyl)bis(2,1-diazenediyl)]bis[N-(2-methylphenyl)-3-oxobutyramide] and 2-[2-[3,3'-dichloro-4'-[2-[1-[[(2-methylphenyl)amino]carbonyl]-2-oxopropyl]diazenyl][1,1'-biphenyl]-4-yl]diazenyl]-3-oxo-N-phenylbutyramide

Results and discussion

Test substance stable:
yes
Transformation products:
not measured

Any other information on results incl. tables

DMSO: very low solubility ¿ solution not stable

Acetone: not soluble

DMF: low solubility ¿ stable for one week

1,4-dioxane: low solubility ¿ stable for one day

Acetonitrile: not soluble

Ethanol: not soluble

Methanol: not soluble

NMP: low solubility, but solution not stable

Remark:

not soluble: filtrate is colorless ¿ no absorption found

very low solubility: filtrate is weak yellow ¿ small absorption

low solubility: solubility is <10mg/100ml

stable: no change of the UV/VIS spectrum during one day or one week

not stable: change of the UV/VIS spectrum during one day or one week (qualitative and/or quantitative)

Applicant's summary and conclusion

Conclusions:
The test item is stable in DMF for one week and stable in 1,4-dioxane for 24 h.
Executive summary:

When tested by UV-vis-spectrometry, The substance was stable in DMF for one week and stable in 1,4-dioxane for 24 h.