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EC number: 273-222-0 | CAS number: 68953-64-0
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Experimental starting date 06 February 2017; Experimental completion date 03 April 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient - Shake Flask Method)
- Version / remarks:
- May 31, 2008
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Version / remarks:
- July 27, 1995
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7550 (Partition Coefficient, n-octanol / H2O, Shake Flask Method)
- Version / remarks:
- August, 1996
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Partition coefficient type:
- octanol-water
- Specific details on test material used for the study:
- Test item 207569/B
Identification Quaternium-26
Appearance Clear amber to dark amber liquid
Batch 0001954899
Composition UVCB
Storage At room temperature
Stable under storage conditions until 22 December 2017 (retest date) - Analytical method:
- other: Since the test item is surface active, the partition coefficient was calculated using the critical micelle concentration and the n-octanol solubility.
- Key result
- Type:
- log Pow
- Partition coefficient:
- >= 3.4
- Temp.:
- 20 °C
- Remarks on result:
- other: pH not measured.
- Details on results:
- After the stirring period, the solution of the test sample in n-octanol was clear lacking undissolved test item. Hence, it was concluded that the n-octanol solubility of at 20°C was ≥ 1016 g/L. The critical micelle concentration was determined to be 0.407 g/L. As a result, the Pow, calculated as the quotient of the n-octanol- and CMC, is ≥ 2.5e3 corresponding with a log Pow value of ≥ 3.4.
- Conclusions:
- The estimation method was applied for the determination of the partition coefficient (Pow) of Quaternium-26. The Pow value of the test item at 20°C was ≥ 2500 corresponding with a log Pow value of ≥ 3.4.
Reference
Description of key information
Based on a guideline study performed under GLP.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 3.4
- at the temperature of:
- 20 °C
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