Registration Dossier

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2016
Report date:
2016

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
Deviations:
yes
Remarks:
The study plan states that the study will be carried out at 18 – 22 °C with a maximum deviation of ±1 °C. However, during the definitive test, the temperatures ranged from 19 – 22 °C, therefore deviating from the study plan. Although this was a deviation,
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
(7-Methoxy-3,4-dihydronaphthalen-1-yl)acetonitrile
EC Number:
617-813-7
Cas Number:
861960-34-1
Molecular formula:
C13H13NO
IUPAC Name:
(7-Methoxy-3,4-dihydronaphthalen-1-yl)acetonitrile

Results and discussion

Effect concentrations
Key result
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
ca. 10 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat. (dissolved fraction)
Basis for effect:
mobility

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
The acute toxicity of the test item to the freshwater invertebrate Daphnia magna has been investigated and gave a 48-Hour EC50 value of 10 mg/l. The No Observed Effect Concentration was 5.5 mg/l.