Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Hydrolysis

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
hydrolysis
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Remarks:
experimental data of read across substances
Justification for type of information:
Data for the target chemical is summarized based on the structurally similar read across chemicals
Reason / purpose for cross-reference:
read-across source
Reason / purpose for cross-reference:
read-across source
Qualifier:
according to guideline
Guideline:
other: as mentioned below
Principles of method if other than guideline:
WoE report is based on two hydrolysis studies as- WoE 1. and WoE-2.
GLP compliance:
not specified
Radiolabelling:
not specified
Analytical monitoring:
not specified
Positive controls:
not specified
Negative controls:
not specified
Transformation products:
not specified
Remarks on result:
other: not hydrolysable due to the lack of hydrolyzable functional groups
Validity criteria fulfilled:
not specified
Conclusions:
The test chemical is not expected to undergo hydrolysis in the environment due to the lack of hydrolyzable functional groups.
Executive summary:

Data available for the structurally and functionally similar read across chemicals has been reviewed from the authoritative database to determine the half-life of the test chemical and their results are mentioned below.

In both the studies the test chemical is not expected to undergo hydrolysis in the environment due to the lack of hydrolyzable functional groups. By considering results of the studies mentioned above it can be concluded that the test chemical is not hydrolysable.

Description of key information

The test chemical is not expected to undergo hydrolysis in the environment due to the lack of hydrolyzable functional groups

Key value for chemical safety assessment

Additional information

Data available for the structurally and functionally similar read across chemicals has been reviewed from the authoritative database to determine the half-life of the test chemical and their results are mentioned below.

In both the studies the test chemical is not expected to undergo hydrolysis in the environment due to the lack of hydrolyzable functional groups.By considering results of the studies mentioned above it can be concluded that the test chemical is not hydrolysable.