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Toxicity to microorganisms

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Reference
Endpoint:
activated sludge nitrification inhibition testing
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Data is from peer reviewed journal
Justification for type of information:
Data is from peer reviewed journal
Qualifier:
according to guideline
Guideline:
other: as mentioned below
Principles of method if other than guideline:
luminiscence reduction test was performed for test material on Photobacterium phosphoreum
GLP compliance:
not specified
Test organisms (species):
other: P. phosphoreum
Test type:
static
Water media type:
freshwater
Total exposure duration:
30 min
Test temperature:
15 deg C
Duration:
30 min
Dose descriptor:
EC50
Effect conc.:
0.22 mg/L
Nominal / measured:
not specified
Conc. based on:
test mat.
Basis for effect:
other: luminiscent
Conclusions:
The effect concentration EC50 of test material on P. phosphoreum was evaluated to be 0.22 mg/l
Executive summary:

Microtox bioassay was performed for the test material on P. phosphoreumbased on the light emission of these bacteria, as a measurement of their metabolic activity. 50% reduction of the light emitted by the bacteria (EC50) is calculated from a concentration response curve by regression analysis. The osmotic pressure of the samples was adjusted by NaCl addition (2%). Toxicity data were based on a 30-min exposure of bacteria to the surfactant solution at 15 deg C. The effect concentration  EC50 of test material on  P. phosphoreum was evaluated to be 0.22 mg/l

Description of key information

Toxicity to microorganism:

Microtox bioassay was performed for the test material onP. phosphoreumbased on the light emission of these bacteria, as a measurement of their metabolic activity. 50% reductionof the light emitted by the bacteria (EC50) is calculated from a concentration response curve by regression analysis. The osmotic pressure of the samples was adjusted by NaCl addition (2%). Toxicity data were based on a 30-min exposure of bacteria to the surfactantsolution at 15 deg C.

Key value for chemical safety assessment

Additional information

Toxicity to microorganism:

Microtox bioassay was performed for the test material onP. phosphoreumbased on the light emission of these bacteria, as a measurement of their metabolic activity. 50% reductionof the light emitted by the bacteria (EC50) is calculated from a concentration response curve by regression analysis. The osmotic pressure of the samples was adjusted by NaCl addition (2%). Toxicity data were based on a 30-min exposure of bacteria to the surfactantsolution at 15 deg C.