Registration Dossier

Diss Factsheets

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
2.4 µg/L
Assessment factor:
50
Extrapolation method:
assessment factor
PNEC freshwater (intermittent releases):
10.6 µg/L

Marine water

Hazard assessment conclusion:
PNEC aqua (marine water)
PNEC value:
0.24 µg/L
Assessment factor:
500
Extrapolation method:
assessment factor

STP

Hazard assessment conclusion:
PNEC STP
PNEC value:
0.895 mg/L
Assessment factor:
100
Extrapolation method:
assessment factor

Sediment (freshwater)

Hazard assessment conclusion:
PNEC sediment (freshwater)
PNEC value:
0.021 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:
PNEC sediment (marine water)
PNEC value:
0.002 mg/kg sediment dw

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
PNEC soil
PNEC value:
0.003 mg/kg soil dw
Extrapolation method:
equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential for bioaccumulation

Additional information

Conclusion on classification

The substance 1-hexyl-1H-pyrazol-4,5-diamine hemisulfate is not readily biodegradable and it is not considered as potentially bioaccumulable due to a log Kow less than 4. The acute aquatic toxicity LC50/EC50 on fish, daphnia and algae are > 1 mg/L and < 10 mg/l. The chronic toxicity is represented by a NOEC of 0.12 mg/L related to the daphnia reproduction test and an EC10 on the algae growth rate of 0.42 mg/L. Taking into account the chronic toxicity on daphnia and algae which is between 0.1 and 1 mg/L, the acute toxity on fish between 1 and 10 mg/L, and the lack of biodegradation, the substance "1 -hexyl-1H-pyrazol-4,5 -diamine hemisulfate" is classified as dangerous to the environment "Aquatic chronic cat. 2" with the hasard statement H411: Toxic to aquatic life with long lasting effects, according to the Regulation N° 1272/2008.