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Diss Factsheets

Physical & Chemical properties

Particle size distribution (Granulometry)

Administrative data

Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
09 Aug 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report date:
2017

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
ISO 13320 (Particle size analysis - Laser diffraction methods)
GLP compliance:
yes
Type of method:
Laser scattering/diffraction

Test material

Constituent 1
Chemical structure
Reference substance name:
Pyridine-2-carboxylic acid
EC Number:
202-719-7
EC Name:
Pyridine-2-carboxylic acid
Cas Number:
98-98-6
Molecular formula:
C6H5NO2
IUPAC Name:
pyridine-2-carboxylic acid

Results and discussion

Particle size
Key result
Percentile:
D50
Mean:
182 µm
St. dev.:
12.4

Any other information on results incl. tables

The results of the two repetitions were:

 

Number of repetition

Median size [x50 (µm)]

Measured value

Average

Relative standard deviation (%)

1

204

182

12.4

2

183

3

159

                                   

Discussion

Three particle size distributions in this study differed somewhat from each other. However, it is considered that the test results were acceptable because the difference of mode size (about 162 µm) was quite low.

Applicant's summary and conclusion