Alcohols, C18-unsatd and ethoxylated C18-unsatd., phosphates (5 moles ethoxylation)

Repeated dose toxicity: inhalation

Administrative data

Endpoint:

short-term repeated dose toxicity: inhalation

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

other:

Cross-reference

Cross-reference 1

Reason / purpose for cross-reference:

data waiving: supporting information

Reference

The physical state and appearance of the test substance were observed during the testing of other endpoint testing (Chilworth, 2017).

Physical state at 20°C and 1013 hPa:

liquid

Yellow, viscous liquid

Cross-reference 2

Reason / purpose for cross-reference:

data waiving: supporting information

Reference

The vapour pressure of the test substance was determined experimentally using isoteniscope method, according to the EU Method A.4, (Chilworth, 2017) as well using QSAR model EPI Suite (US EPA, 2018).

Vapour pressure:

0 Pa

at the temperature of:

25 °C

- Experimental VP = <100 Pa at 20 °C (using isoteniscope method); not suitable for multi-constituents/UVCB substances.

- Weighted average QSAR based VP = 1.44E-8 Pa at 25°C (using EPI Suite v.4.11). The estimates for the major constituents are considered to be reliable with restrictions, as they do not completely fall within of the applicability domain.

Overall, based on the above information, the test substance can be considered to have low volatility. However, in absence of a specific value from the experimental study and considering that isoteniscope method is not suitable for multi-constituents/UVCB substances, the QSAR based VP value of 1.44E-8 Pa, has been considered further for hazard/risk assessment.