Registration Dossier
Registration Dossier
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EC number: 231-185-8 | CAS number: 7443-25-6
Endpoint summary
Administrative data
Description of key information
Hydrolysis half-life at 12°C, pH 7: 102 d (calculated acc. to ECHA guidance R.16, OECD 111, 2016)
Additional information
In a reliable key study, hydrolysis as a function of pH was determined according to OECD 111 and in compliance with GLP (RL1). Hydrolysis reaction rate constants and half-lives of the submission substance were calculated from analysed samples based on a first order reaction kinetics model. The submission substance hydrolysed slowly (half-life t1/2 > 30 d) at pH 4 and 7 at 20 °C and moderately (2.4 h ≤ t1/2 ≤ 30 d) for the remaining test conditions (pH 4 at 30 and 50 °C, pH 7 at 30 and 50 °C as well as for pH 9 at 20, 30 and 50 °C). Half-lives were shorter in alkaline conditions (higher pH). The derived key value for exposure assessment was 102 days at 12°C, pH 7 (calculated acc. to ECHA guidance R.16). The test was considered reliable and adequate for the environmental fate assessment of the submission substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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