Registration Dossier
Registration Dossier
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EC number: 451-530-8 | CAS number: 736150-63-3
Endpoint summary
Administrative data
Description of key information
Additional information
The bioaccumulation potential of TS-ED 532 was tested in zebra fish larvae (Danio rerio) using a modified in-vitro procedure based on the OECD Guideline for Testing of Chemicals No. 305 “Bioconcentration: Flow-through Fish Test", which corresponds to the EU Testing Method C.13 Bioconcentration: Flow-through fish test. Based on the mean BCFss results, a conservative estimate of BCF was 981 ± 330, resulting in a log BCF of 2.99 ± 0.14. These data show that TS-ED 532 is moderately concentrating in fish by testing at the yolk sac larval stage but residues would appear to have been specifically retained in the yolk tissue. As biotransformation of xenobiotics in embryonic and larval stages has been shown to be insignificant compared to juvenile/adult stages, higher body burdens of readily biotransformed chemicals may be reached in early life stages of fish. These data could indicate a potential for bioaccumulation of TS-ED 532 in the environment.
Overall, TS-ED 532 has a high partition coefficient which is characteristic of a bioaccumulative substance. However, as it is a glyceride and therefore inherently metabolizable, bioaccumulation is not expected. Based on the results from the biodegradation study, TS-ED 532 is readily biodegradable and not expected to persist in the environment.
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