Registration Dossier
Registration Dossier
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EC number: 451-530-8 | CAS number: 736150-63-3
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
TS-ED 532 was shown not to have inhibitory effects on the reproduction of the freshwater crustacean Daphnia magna up to 70 µg/L. and therefore, the NOEC (21 days) is estimated to be≥70 µg/L and the EC10 as well as EC50 are estimated to be >70 µg/L..
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 70 µg/L
Additional information
TS-ED 532 was tested for inhibitory effects on the reproduction of the freshwater crustacean Daphnia magna according to the OECD Guideline for Testing of Chemicals No. 211, DS/ISO Standard 10706 and EEC Annex V tests C20. Due to the very low water solubility of TS-ED 532, the study was conducted with radiolabelled TS-ED 532 using concentrations of 10; 16; 27; 43 and 70 µg/L. According to preliminary studies, 70 µg/L (60-90 µg/L) was the highest concentration of TS-ED 532 to be dissolved in the test medium. Acetone was used as a solvent. The production of offspring was uniform in both controls compared with the individual test concentrations, and therefore, the NOEC (21 days) is estimated to be≥70 µg/L and the EC10 as well as EC50 are estimated to be >70 µg/L.
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