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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Link to relevant study record(s)

Description of key information

Not acute toxic to bacteria.
NOEC (3h) < 125 mg/L
EC20 (3h) = 270 mg/L 
3h EC50 > 2000 mg/L 
EC10(16 h) = 2600 mg/L
EC50(16 h) = 7500 mg/L

Key value for chemical safety assessment

EC50 for microorganisms:
2 000 mg/L

Additional information

Two studies were determined. In the key study two valid experiments were performed:

First, a limit-test with two replicates using the nominal concentration 1,000 mg/L

The treatment 1,000 mg/L showed a mean inhibition of the respiration rate of the activated sludge of 31%.

Then, a main study was performed using five concentrations ranging from 2,000 to 125 mg/L.

The following inhibitions of the respiration rate of the activated sludge were detected: At 2000 mg/L 29.5 %, at 1000 mg/L 30.0 %, at 500 mg/L 24.5 %, at 250 mg/L 19.5 % and at 125 mg/L 15.8% inhibition were detected.

The following results for the test item were determined:

NOEC (3h) < 125 mg/L

EC20 (3h) = 270 mg/L (95% confidence interval: 110 - 430 mg/L)

EC50 (3h) > 2000 mg/L

In the supporting study the following values were determined:

EC10(16 h) = 2600 mg/L

EC50(16 h) = 7500 mg/L

The substance is not acute toxic for bacteria.