Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 200-252-3 | CAS number: 56-04-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Guidance on Safe Use
Administrative data
First-aid measures
Eyes: Immediately flush eyes with copious quantities of water for at least 15 minutes holding lids apart to ensure flushing of the entire surface. Seek medical attention if irritation persists.
Skin: Wash off immediately with soap and plenty of water while removing all contaminated clothes and shoes. Seek medical attention if irritation persists. Launder contaminated clothing before reuse.
Ingestion: Do not induce vomiting. Never give anything by mouth to an unconscious person. Drink plenty of water. Rinse mouth with water. Seek medical attention. If possible drink milk afterwards.
Inhalation: If breathed in, remove from exposure and move the person to fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration. Consult a physician.
Fire-fighting measures
Extinguishing Media: Alcohol-resistant foam, dry chemical, carbon dioxide or water spray.
Special hazards arising from the substance or mixture: Danger of decomposition under influence of heat. Harmful vapours Evolution of fumes/fog.
Fire Fighting Equipment/Instructions: In case of fire, remove the endangered containers and bring to a safe place, if this can be done safely. In case of fire cool containers or take them to a safe place. Contaminated extinguishing water must be treated at a suitable disposal plant in accordance with waste management laws. Take precautionary measures against static discharges. Ensure there are sufficient retaining facilities for water used to extinguish fire. Fire residues should be disposed of in accordance with the regulations. Keep out unprotected persons.
Accidental release measures
Personal precautions, protective equipment and emergency procedures: Put on appropriate personal or protective equipment. Evacuate surrounding areas. Ensure adequate ventilation. No action shall be taken involving any personal risk or without suitable training. Remove all sources of ignition Heat, flames and sparks. Avoid creating dust. Avoid contact with the skin and the eyes. Ensure adequate ventilation.
Containment Procedures: Prevent entry into sewers and waterways. Do not flush into surface water or sanitary sewer system.
Clean-up Procedures: Absorb with inert material (e.g. dry sand or earth), and place in a clearly labelled container for chemical waste. Do not flush with water.
Special Procedures: Personal protective equipment must be worn: Fully protective suit, Respiratory protective device, Helmets, Protective Boots and Gloves. Ventilate area if spilled in a confined space or other poorly ventilated area.
Handling and storage
Handling Procedures: Keep containers closed when not in use. Avoid contact with skin and eyes. In case of insufficient ventilation, wear suitable respiratory equipment. Do not eat, drink or smoke when using this product. Wear personal protective equipment. Launder contaminated clothing before reuse. Empty container contains product residue which may exhibit hazards of product. Dispose of packing or containers in accordance with local, regional, national and international regulations.
Storage Procedures: Keep away from open flames, hot surfaces and sources of ignition. Avoid dust accumulation in enclosed space. Store in a tightly closed container, store in a cool dry well-ventilated area away from incompatible substance. Container should be properly labelled. Do not store near acids.
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- Not Dangerous Goods
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Inland waterway transport (UN RTDG/ADN(R))
- UN number:
- Not Dangerous Goods
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Marine transport (UN RTDG/IMDG)
- UN number:
- Not Dangerous Goods
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Air transport (UN RTDG/ICAO/IATA)
- UN number:
- Not Dangerous Goods
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Exposure controls / personal protection
Control of dermal exposure: Handle with rubber gloves, coveralls, apron, boots as necessary to minimize contact. Gloves should be inspected prior to use and have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Use proper glove removal technique to avoid skin contact. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Control of eye/face exposure: Safety eyewear complying with an approved standard should be used when a risk assessment indicates this is necessary to avoid exposure to liquid splashes, mists, gases or dusts.
Control of inhalation exposure: Use respirator with a combination organic vapor and high efficiency filter cartridge if recommended exposure limit is exceeded (e.g. dust mask type N95 (US) or type P1 (EN 143) respirator). Use self-contained breathing apparatus for entry into confined space, for other poorly ventilated areas and for large spill clean-up sites. A respiratory protection program compliant with all applicable regulations must be followed whenever workplace conditions require the use of a respirator.
General: Wash thoroughly after handling this product Eye wash fountain and emergency showers are recommended.
Control of environmental exposure: Do not let product enter into sewers, waterways or ground water system.
Stability and reactivity
Chemical Stability: Stable under normal conditions.
Conditions to Avoid: Avoid all possible sources of ignition (spark or flame). Do not pressurise, cut, weld, braze, solder, drill, grind or expose containers to heat or sources of ignition.
Incompatibility: Oxidizing materials.
Disposal considerations
Waste should only be disposed of via a licensed waste contractor. The European Waste Catalogue (EWC) and European Waste List
(EWL) is a harmonized list of wastes. Waste materials should be classified prior to final disposal with EWC-codes. Wastes and empty containers should be treated based on their classification and properties referring to local and national waste management regulations. Waste management options: Dispose of to non-hazardous or hazardous waste landfill (Council Directive on the landfill of waste 99/31/EU and Council Decision establishing criteria and procedures for the acceptance of waste at landfills 2003/33/EU) or dispose of via hazardous waste incineration.
The generation of waste should be avoided or minimized wherever possible. Dispose of surplus and non-recyclable products via a licensed waste disposal contractor. Disposal of this product, solutions and any by-products should at all times comply with the requirements of environmental protection and waste legislation and any local waste management regulations.
Waste codes should be assigned by the user, preferably in discussion with the waste disposal authorities. All wastes containing residues of the substance or its hazardous degradation products shall be classified as hazardous waste.
All wastes containing residues of the substance or its hazardous degradation products should be disposed of as hazardous waste to authorized hazardous waste incineration plants, operated according to Directive 2008/98/EC on waste, Directive 2000/76/EC on the incineration of waste and Best Available Techniques for Waste Incineration as described in the respective BREF of August 2006.
Contaminated packaging: Contaminated packaging should be emptied as far as possible and disposed of as hazardous waste to
incineration plants in accordance with Directive 2000/76/EC. Clean packaging material should be subjected to waste management schemes (recovery, recycling, re-use) according to local waste management regulations.
The substance and its container must be disposed of in a safe way. Care should be taken when handling emptied containers that have not been cleaned or rinsed out. Empty containers or liners may retain some product residues. Avoid dispersal of spilt material and runoff and contact with soil, waterways, drains and sewers.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.

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