N,N'-[(methylimino)dipropane-1,3-diyl]dioleamide

Solubility in organic solvents / fat solubility

Link to relevant study record(s)

Reference

Endpoint:

solubility in organic solvents / fat solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2017-03-03 to 2017-09-25

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

equivalent or similar to guideline

Guideline:

other: OECD guideline 105

Deviations:

not applicable

Principles of method if other than guideline:

The test item was analysed for n-octanol solubility, using a procedure based on the shakeflask method described in OECD guideline 105.

GLP compliance:

no

Key result

Medium:

n-octanol

Solubility:

250 g/L

Temp.:

20 °C

Remarks on result:

other: estimated from preliminary study

Details on results:

The test item was analysed for 1-Octanol solubility, using a procedure based on the shake flask method described in OECD 105.
The test mixtures separated in two phases, a solid upper phase, and a cloudy gel-like lower phase.
These mixtures could not be separated to isolate a saturated 1-Octanol solution.
It was not possible to determine the 1-Octanol solubility using the shake-flask procedure as described in OECD 105.
For this reason, the results obtained in the preliminary test were used to estimate the 1-octanol solubility of the test item (refer to table below).

Results obtained in the preliminary test were used to estimate the l-Octanol solubility ofthe test item.

Experiment	Amount 1 -Octanol [ml]	Weighed Sample [mg]	Result
A	2.0	7.4	clear
B	2.0	59.3	clear
C	2.0	243.8	clear
D	2.0	501.2	minor undissolved particles
E	2.0	1021.8	minor undissolved particles
F	2.0	1982.0	cloudy with small particles
G	2.0	3099.2	homogeneous solid material formed

Conclusions:

1-Octanol solubility ofN,N'-[(methylimino)bis(trimethylene)] bis(oleamide) at 20 °C is estimated to 250 g/l.

Executive summary:

The solubility of N,N'-[(methylimino)bis(trimethylene)] bis(oleamide) in 1-Octanol was measured according to OECD Guideline 105 (27 July 1995) using the flask method at 20 °C.

The test mixtures separated in two phases, a solid upper phase, and a cloudy gel-like lower phase.

These mixtures could not be separated to isolate a saturated 1-Octanol solution. It was not possible to determine the 1-Octanol solubility using the shake-flask procedure as described in OECD 105.

For this reason, the results obtained in the preliminary test were used to estimate the 1-Octanol solubility of the test item.

1-Octanol solubility ofN,N'-[(methylimino)bis(trimethylene)] bis(oleamide) at 20 °C is estimated to 250 g/l.

Description of key information

1-Octanol solubility ofN,N'-[(methylimino)bis(trimethylene)] bis(oleamide) at 20 °C is estimated to 250 g/l.

Key value for chemical safety assessment

At the temperature of:

20 °C

Solubility in organic solvents at 20°C:

250 g/L

Additional information

The solubility of N,N'-[(methylimino)bis(trimethylene)] bis(oleamide) in n-Octanol was measured according to OECD Guideline 105 (27 July 1995) using the flask method at 20 °C.

The test mixtures separated in two phases, a solid upper phase, and a cloudy gel-like lower phase.

These mixtures could not be separated to isolate a saturated 1-Octanol solution. It was not possible to determine the 1-Octanol solubility using the shake-flask procedure as described in OECD 105.

For this reason, the results obtained in the preliminary test were used to estimate the 1-Octanol solubility of the test item.

1-Octanol solubility ofN,N'-[(methylimino)bis(trimethylene)] bis(oleamide) at 20 °C is estimated to 250 g/l.