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Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
28 October 2008 - 19 December 2008
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: This study has been performed according to OECD and EC guidelines and according to GLP principles.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2009
Report date:
2009

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method

Test material

Constituent 1
Chemical structure
Reference substance name:
2-[2-(carboxymethyl)phenoxy]-3,4-dimethylbenzoic acid
EC Number:
601-485-7
Cas Number:
117570-93-1
Molecular formula:
C17 H16 O5
IUPAC Name:
2-[2-(carboxymethyl)phenoxy]-3,4-dimethylbenzoic acid
Constituent 2
Reference substance name:
2-(6-carboxy-2,3-dimethylphenoxy)-benzeneacetic acid
IUPAC Name:
2-(6-carboxy-2,3-dimethylphenoxy)-benzeneacetic acid
Details on test material:
Identification: ASA404 C7
Molecular formula: C17H16O5
Molecular weight: 300.31
CAS Number: 117570-93-1
Description: Off white powder (determined at NOTOX)
Batch: 072301
Purity: 99.9%
Test substance storage: At room temperature in the dark
Stability under storage conditions: Stable
Expiry date: 18 March 2009

Results and discussion

Water solubility
Water solubility:
18 mg/L
Temp.:
19.9 °C
pH:
5.2

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
The flask method was chosen for the determination of the water solubility of ASA404 C7. The water solubility of the test substance at 19.9 ± 0.6°C
was 18.0 mg/l. The pH of the aqueous sample after 72 hours stirring was 5.2.

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