Registration Dossier
Registration Dossier
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EC number: 215-657-0 | CAS number: 1338-02-9
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Aquatic toxicity studies of copper naphthenate are not available. Thus, read-across to the assessment entities soluble copper substances and naphthenic acid is applied since the ions of copper naphthenate determine its fate and toxicity in the environment. Regarding copper, a 30-d NOEC of 0.23 mg dissolved Cu/L (inhibition of total respiration / respiration rate) was determined for microorganisms based on a weight-of-evidence approach and five studies. Data for naphthenic acid point to low toxic potential to aquatic microorganisms since an inhibition was not observed up to and at 100 mg/L in a biodegradation test. However, studies on Vibrio fisheri produced an EC50 of 13.0 mg/L for the structural analogue of naphthenic acid, i.e. cyclohexanepentanoic acid. Therefore, based on the toxicity of its dissociation products and analogue substances, copper naphtenate has potential for toxicity to microorganisms.
Key value for chemical safety assessment
Additional information
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