Registration Dossier
Registration Dossier
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EC number: 943-224-2 | CAS number: -
Endpoint summary
Administrative data
Description of key information
A high quality, guideline- and GLP-compliant 28-day oral rat study is available. |
Key value for chemical safety assessment
Repeated dose toxicity: via oral route - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- NOAEL
- 1 000 mg/kg bw/day
- Study duration:
- subacute
- Species:
- rat
- Quality of whole database:
- A high quality, guideline- and GLP-compliant 28-day rat study is available. A waiver is proposed for the 90-day study in the absence of any effects in the 28-day study and as systemic exposure is unlikely.
Repeated dose toxicity: inhalation - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
- Quality of whole database:
- No study is available.
Repeated dose toxicity: inhalation - local effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
- Quality of whole database:
- No study is available.
Repeated dose toxicity: dermal - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
- Quality of whole database:
- No study is available.
Repeated dose toxicity: dermal - local effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
- Quality of whole database:
- No study is available.
Additional information
No effects of treatment were observed in a 28 -day oral (gavage) rat study at the limit dose of 1000 mg/kg bw/d. A waiver is proposed for the 90-day study in the absence of any effects in the 28-day study and as systemic exposure is unlikely. |
Justification for classification or non-classification
The substance is of very low toxicity following repeated oral exposure; the available data do not warrant classification for STOT-RE under the CLP Regulation. |
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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