Registration Dossier
Registration Dossier
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EC number: 602-997-3 | CAS number: 124495-18-7
Endpoint summary
Administrative data
Description of key information
No significant hydrolytic degradation was observed to occur in pH buffers 5, 7 or 9 at 50°C. Less than 10% hydrolysis was observed at 5 days which by the guidelines defines the substance as hydrolytically stable (t1/2> 1 year). In another test at pH 4, the test substance degraded at 25°C with a t1/2 of 11 weeks, decreasing to ca 2 weeks at 40°C and in a third test, the half-life at pH 4 and 50°C was 5 days. 5,7-dichloro-4-hydroxyquinoline (DCHQ) was found to be the hydrolysis product. In phototransformation studies in water, the test substance degraded with a ½ life of 18 minutes. CFBPQ (2-chloro-10-fluoro[1]benzopyrano[2,3,4-de]quinoline) was identified as the primary photodegradate of the test substance.
CFBPQ is formed very quickly under natural conditions. Once formed there is a rapid degradation of CFBPQ to material which is polar and multicomponent in nature. When sediment is present the amount of radioactivity present in the aqueous layer is greatly reduced due to partitioning of CFBPQ to the sediment. Low water solubility combined with rapid aqueous photolysis suggest that the test substance will have minimal impact on the aquatic environment. The t1/2 estimated for test substance under natural sunlight conditions (>1 year; spring at Letcombe, England) has indicated that soil photolysis will not be a significant route of degradation for the test substance in the environment.
Additional information
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