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Environmental fate & pathways

Biodegradation in water: screening tests

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Reference
Endpoint:
biodegradation in water: ready biodegradability
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
GLP compliance:
yes (incl. QA statement)
Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge (adaptation not specified)
Duration of test (contact time):
28 d
Initial conc.:
100 mg/L
Parameter followed for biodegradation estimation:
CO2 evolution
Parameter followed for biodegradation estimation:
O2 consumption
Reference substance:
benzoic acid, sodium salt
Key result
Parameter:
other: ThOD
Remarks:
Mean
Value:
1.03
Sampling time:
28 d
Details on results:
Percentage biodegradation at 28 days :
- exp 1 = 0%
- exp 2 = 0.88 %
- exp 3 = 2.20%
- control 1 = 28.99%
- control 2 = 30.91%
- reference substance 1 = 94.35%
- reference substance 2 = 97.34%
Validity criteria fulfilled:
no
Remarks:
variation between the test item replicates > 20%. The data of the first test are not presented.
Interpretation of results:
not readily biodegradable
Conclusions:
The biodegradation potential was determined according to the OECD 301F guideline. Based on the ThOD, the 10-day window failed and the degradation rate of the test item is 1.30% after 28 days. Regarding this result, the test item is not considered to be biodegradable.
Executive summary:

The biodegradation potential was determined according to the OECD 301F guideline. Based on the ThOD, the 10-day window failed and the degradation rate of the test item is 1.30% after 28 days. Regarding this result, the test item is not considered to be biodegradable.

Description of key information

The biodegradation potential was determined according to the OECD 301F guideline. Based on the ThOD, the 10-day window failed and the degradation rate of the test item is 1.30% after 28 days. Regarding this result, the test item is not considered to be biodegradable.

Key value for chemical safety assessment

Biodegradation in water:
under test conditions no biodegradation observed
Type of water:
freshwater

Additional information