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Environmental fate & pathways

Biodegradation in water: screening tests

Administrative data

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
experimental study
Adequacy of study:
key study
Study period:
19.10 - 04.12.2000
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: study according to GLP guidline and OECD 301B
Cross-referenceopen allclose all
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
reference to other study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2000

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
Deviations:
no
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
1,5-dihydro-3-isopropyl-8-methyl-[1,3]dioxepino[5,6-c]pyridin-9-yl acetate
EC Number:
296-417-2
EC Name:
1,5-dihydro-3-isopropyl-8-methyl-[1,3]dioxepino[5,6-c]pyridin-9-yl acetate
Cas Number:
92671-67-5
Molecular formula:
C14H19NO4
IUPAC Name:
8-methyl-3-(propan-2-yl)-1H,3H,5H-[1,3]dioxepino[5,6-c]pyridin-9-yl acetate
Details on test material:
-

Study design

Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge, domestic (adaptation not specified)
Duration of test (contact time):
28 d
Initial test substance concentration
Initial conc.:
20 mg/L
Based on:
DOC

Results and discussion

% Degradation
Parameter:
% degradation (CO2 evolution)
Value:
19
Sampling time:
28 d
Details on results:
substance is not readily biodegradable

Any other information on results incl. tables

no overall remarks

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Interpretation of results:
other: not readily biodegradable
Conclusions:
Substance is not readily biodegradable
Executive summary:

Isobutyralacetate was tested for its ready biodegradability in the CO2 evolution test (Modified Sturm Test)

The study procedure was based on OECD guideline No. 301 B, July 17, 1992.

The test piece was added in a quantity of 20 mg/l DOC to the test medium.

The inoculum was derived from the secondary effluent of a treatment plant. Anillin was used as reference substance. The observed biodegradability was 19% after 28 days.

The criterion for ready biodegradability (at least 70% removal of DOC in a 10 -day window) was not met in these experiment.

The substance was found to be not readily biodegradable.