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Physical & Chemical properties

Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
ISO 13320 (Particle size analysis - Laser diffraction methods)
Version / remarks:
2009
Qualifier:
according to guideline
Guideline:
other: CIPAC MT 187
Version / remarks:
2007
GLP compliance:
yes (incl. QA statement)
Type of method:
Laser scattering/diffraction
Type of particle tested:
primary particle
Type of distribution:
mass based distribution
Specific details on test material used for the study:
Batch : TROD7BB06
Mass median aerodynamic diameter:
264 µm
Geometric standard deviation:
1.709
Key result
Percentile:
D10
Mean:
97.4 µm
St. dev.:
0.978
Key result
Percentile:
D50
Mean:
204 µm
St. dev.:
0.898
Key result
Percentile:
D90
Mean:
407 µm
St. dev.:
2.39

0.0 % by volume of sample was seen to be < 10.00 μm

Conclusions:
The test item has been analyzed using a visual microscope and more formally using a Laser Diffraction Particle Size Analyser with the following results (mean ± st dev) :
D10 : 97.4 ± 0.978 μm
D50 : 204 ± 0.898 μm
D90: 407 ± 2.39 μm
MMAD: 264 ± 1.041 µm
No particles were detected with a diameter <10 µm.
Executive summary:

The test item has been analyzed using a visual microscope and more formally using a Laser Diffraction Particle Size Analyser with the following results (mean ± st dev) :

D10 : 97.4 ± 0.978 μm

D50 : 204 ± 0.898 μm

D90: 407 ± 2.39 μm

MMAD: 264 ± 1.041 μm

No particles were detected with a diameter <10 µm.

Description of key information

The test item has been analyzed using a visual microscope and more formally using a Laser Diffraction Particle Size Analyser with the following results (mean ± st dev) :

D10 : 97.4 ± 0.978 μm

D50 : 204 ± 0.898 μm

D90: 407 ± 2.39 μm

MMAD: 264 ± 1.041 μm

No particles were detected with a diameter <10 µm.

Additional information