Registration Dossier
Registration Dossier
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EC number: 671-273-7 | CAS number: 22245-83-6
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Peer review of the pesticide risk assessment of the active substance flazasulfuron
- Author:
- European Food Safety Authority (EFSA)
- Year:
- 2 016
- Bibliographic source:
- EFSA Journal 2016;14(8):4575
Materials and methods
- Principles of method if other than guideline:
- - Principle of test:
not reported
- Short description of test condtions: not reported
- Parameters analysed / observed: acute oral toxicity in the rat - GLP compliance:
- not specified
- Test type:
- other: not specified
Test material
- Reference substance name:
- 3-(trifluoromethyl)pyridin-2(1H)-one
- EC Number:
- 671-273-7
- Cas Number:
- 22245-83-6
- Molecular formula:
- C6H4F3NO
- IUPAC Name:
- 3-(trifluoromethyl)pyridin-2(1H)-one
- Test material form:
- not specified
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- not specified
- Doses:
- at least one dose level at 2000 mg/kg bw
- No. of animals per sex per dose:
- not specified
- Control animals:
- not specified
Results and discussion
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Based on:
- test mat.
- Mortality:
- not reported
- Clinical signs:
- other: not reported
- Gross pathology:
- not reported
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- The oral LD50 value of the test material in rats was reported to be >2000 mg/kg bw.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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