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Long-term toxicity to aquatic invertebrates

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Reference
Endpoint:
long-term toxicity to aquatic invertebrates
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
accepted calculation method
Justification for type of information:
Data is from ECOSAR version 1.11
Qualifier:
according to guideline
Guideline:
other: Modeling database
Principles of method if other than guideline:
ECOSAR v1.1
GLP compliance:
no
Specific details on test material used for the study:
IUPAC name: 1-phenylethan-1-ol
Mol. formula: C8H10O
Molecular Weight: 122.166 g/mol
Substance form: Colourless liquid
Substance type: organic
InChI: 1S/C8H10O/c1-7(9)8-5-3-2-4-6-8/h2-7,9H,1H3
Smiles :c1(ccccc1)C(C)O
Test organisms (species):
Daphnia magna
Test type:
not specified
Water media type:
not specified
Key result
Duration:
21 d
Dose descriptor:
NOEC
Effect conc.:
13.28 mg/L
Nominal / measured:
estimated
Conc. based on:
test mat.
Basis for effect:
immobilisation
Remarks on result:
other: ECOSAR v1.11
Validity criteria fulfilled:
not specified
Conclusions:
On the basis of effects observed in a static freshwater system, the NOEC value for the substance is estimated to be 13.280 mg/l for aquatic invertebrate for 21 days of exposure duration.
Executive summary:

Based on the prediction done using ECOSAR version 1.1, the long term toxicity on aquatic invertebrate was predicted for test substance . On the basis of effects observed in a static freshwater system, the NOEC value for the substance 1-phenylethan-1 ol(98 -85 -1) is estimated to be 13.280 mg/l for aquatic invertebrate for 21 days of exposure duration.Since, the test substance is readily biodegradable , it can be concluded that the test chemical 1-phenylethan-1 ol(98 -85 -1) can be considered as non-toxic to aquatic invertebrate at environmentally relevant concentrations and can be considered not-classified as per the CLP classification criteria.

Description of key information

Long term toxicity to aquatic invertebrate:

Based on the prediction done using ECOSAR version 1.1, the long term toxicity on aquatic invertebrate was predicted for test substance . On the basis of effects observed in a static freshwater system, the NOEC value for the substance 1-phenylethan-1 ol(98 -85 -1) is estimated to be 13.280 mg/l for aquatic invertebrate for 21 days of exposure duration.Since, the test substance is readily biodegradable , it can be concluded that the test chemical 1-phenylethan-1 ol(98 -85 -1) can be considered as non-toxic to aquatic invertebrate at environmentally relevant concentrations and can be considered not-classified as per the CLP classification criteria.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
13.28 mg/L

Additional information

Long term toxicity to aquatic invertebrate:

Based on the prediction done using ECOSAR version 1.1, the long term toxicity on aquatic invertebrate was predicted for test substance . On the basis of effects observed in a static freshwater system, the NOEC value for the substance 1-phenylethan-1 ol(98 -85 -1) is estimated to be 13.280 mg/l for aquatic invertebrate for 21 days of exposure duration.Since, the test substance is readily biodegradable , it can be concluded that the test chemical 1-phenylethan-1 ol(98 -85 -1) can be considered as non-toxic to aquatic invertebrate at environmentally relevant concentrations and can be considered not-classified as per the CLP classification criteria.