Registration Dossier
Registration Dossier
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EC number: 952-395-2 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Short-term toxicity to fish
LC50 (96h) = 77.3 mg/l
Short-term toxicity to aquatic invertebrates
EC50 > 220 mg/l
Toxicity to aquatic plants other then algae
ECr50 > 2540 mg/L.
Additional information
Adequate chronic toxicity data are not available for the target substance, therefore the aquatic toxicity assessment and classification are based mainly on the short-term toxicity data available.
Despite the target substance has a log kow lower than 4 (indicating a low potential for bioaccumulation), it is not rapidly degradable.
According to the CLP Regulation (EC n. 1272/2008) acute aquatic toxicity is normally determined using a fish 96 hours LC50, a crustacea species 48 hours EC and/or an algal species 72 or 96 hour EC50, nevertheless it is also specified in the Regulation that data on other species (e.g. Lemna spp.) shall also be considered if the test methodology is suitable.
These species cover a range of trophic levels and taxa and are considered as surrogate for all aquatic organisms.
Data are available for fish (Brachydario Rerio), Daphnia Magna and Algae:
6.1.1 - Short-term toxicity to fish
No studies on "short-term toxicity to fish" are available on the Target Substance. However information on similar substances has been used for the assessment.
The result of the acute toxicity test carried out on Similar Substance 03 showed some effects to fish.
The species used in the key test was Poecilia Reticulata and the concentration were: 100, 75, 50 and 25 mg/l.
The results of the test were:
- 48h LC50 = 80 mg/l
- 96h LC50 = 77,3 mg/l
The presence of toxic effects for fish is confirmed by the results of the supporting study conducted on Similar Substance 02.
6.1.3 -Short-term toxicity to aquatic invertebrate
The study used to cover this endpoint (Daphnia Magna) has been conducted on Similar Substance 01 and shows an EC50 value greater than 220 mg/l.
6.1.6 – Toxicity to aquatic plants other then algae
The study used to cover this endpoint (Lemna Minor) has been conducted on Similar Substance 01 and shows an EC50 > 2540 mg/L.
6.1.7 - Toxicity to microorganisms
Three studies are available on Similar Substnace 01 regarding the toxicity to microorganisms. The study selected as key study shows an EC50 value greater then 10000 mg/l, the others are short summaries and show EC50 > 1000,0 mg/l.
Based on the criteria of the CLP Regulation EC n. 1272/2008, the susbtance is classified asAquatic Chronic 3, H412.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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