4-fluoroaniline

Biodegradation in soil

Administrative data

Endpoint:

biodegradation in soil

Type of information:

migrated information: read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Review of existing data and read-across

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1998

Report date:

1998

Materials and methods

Test guideline

Qualifier:

no guideline followed

GLP compliance:

no

Test type:

laboratory

Test material

Test material information

Constituent 1

Reference substance name:

4-fluoroaniline

EC Number:

206-735-5

EC Name:

4-fluoroaniline

Cas Number:

371-40-4

Molecular formula:

C6H6FN

IUPAC Name:

4-fluoroaniline

Constituent 2

Reference substance name:

Reference substance 002

EC Number:

604-030-0

Study design

Oxygen conditions:

aerobic

Soil classification:

other: loamy sand

Details on soil characteristics:

German standard soil 2.2

Duration of test (contact time)

Duration:

152 d

Details on experimental conditions:

The parent compound N-(4-Fluoro-phenyl)-6-[3-trifluoromethyl)phenoxy]-2-pyridine-carboxamide labelled in the aniline ring was applied to a German standard soil equally to a field rate of 100 g/ha. The soil was aerobically incubated for 152 days. Soils samples were extracted with appropriate solvents. A rapid degradation of the parent compound was observed. Although, the samples were exhaustively extracted, neither 4-fluoroaniline nor any other degradation product exceeding 5 % of applied was detected in the extracts. Only be using a very harsch ectraction method a low level of 4-fluoroaniline was detected. The study showed that 4-fluoroaniline is strongly bound to soil and finally mineralised to CO2.

Furthermore, public available data of chloroanilines were used for a read-across to 4-fluoroaniline. The data confirms a short dissipation half-live for these compounds followed by a subsequent and ultimate degradation to CO2.