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EC number: 941-379-0 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: This study is classified as reliable with restrictions because it is an acceptable and well-documented study report.
- Justification for type of information:
- Read across justification included in Section 13
Cross-reference
- Reason / purpose for cross-reference:
- read-across: supporting information
Reference
- Endpoint:
- acute toxicity: dermal
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: This study is classified as reliable with restrictions because it is an acceptable and well-documented study report.
- Justification for type of information:
- Read across justification included in Section 13
- Reason / purpose for cross-reference:
- read-across source
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 402 (Acute Dermal Toxicity)
- GLP compliance:
- yes
- Test type:
- other: API procedure
- Species:
- rabbit
- Strain:
- New Zealand White
- Sex:
- male/female
- Type of coverage:
- not specified
- Vehicle:
- other: Undiluted
- Duration of exposure:
- 24 hours
- Doses:
- Single dose of 2000 mg/kg
- No. of animals per sex per dose:
- Four
- Control animals:
- not specified
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The LD50 was greater than 2000 mg/kg.
- Executive summary:
A group of 4 male and 4 female New Zealand White rabbits was tested at a single dose of 2000 mg/kg. The skins of 2 male and 2 female animals were abraded prior to treatment. Animals were observed for 14 days following the 24-hour exposure period. No deaths resulted. At necropsy, irritated skin at the treatment site was noted in one animal, and pitted areas on the kidneys in two animals. The LD50 was greater than 2000 mg/kg
No deaths resulted. At necropsy, irritated skin at the treatment site was noted in one animal, and pitted areas on the kidneys in two animals.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 982
- Report date:
- 1982
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 402 (Acute Dermal Toxicity)
- GLP compliance:
- yes
- Test type:
- other: API procedure
Test material
- Reference substance name:
- Kerosine (petroleum), hydrodesulfurized
- EC Number:
- 265-184-9
- EC Name:
- Kerosine (petroleum), hydrodesulfurized
- Cas Number:
- 64742-81-0
- IUPAC Name:
- Kerosine (petroleum), hydrodesulfurized
- Reference substance name:
- Hydrodesulfurised kerosine
- IUPAC Name:
- Hydrodesulfurised kerosine
- Test material form:
- other: low viscosity liquid hydrocarbon
- Details on test material:
- - Name of test material (as cited in study report): Hydrodesulfurised kerosine, CAS No. 64742-81-0
- Lot/batch No.: API 81-07
Constituent 1
Constituent 2
Test animals
- Species:
- rabbit
- Strain:
- New Zealand White
- Sex:
- male/female
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- other: Undiluted
- Duration of exposure:
- 24 hours
- Doses:
- Single dose of 2000 mg/kg
- No. of animals per sex per dose:
- Four
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
Any other information on results incl. tables
No deaths resulted. At necropsy, irritated skin at the treatment site was noted in one animal, and pitted areas on the kidneys in two animals.
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The LD50 was greater than 2000 mg/kg.
- Executive summary:
A group of 4 male and 4 female New Zealand White rabbits was tested at a single dose of 2000 mg/kg. The skins of 2 male and 2 female animals were abraded prior to treatment. Animals were observed for 14 days following the 24-hour exposure period. No deaths resulted. At necropsy, irritated skin at the treatment site was noted in one animal, and pitted areas on the kidneys in two animals. The LD50 was greater than 2000 mg/kg
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