Registration Dossier
Registration Dossier
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Diss Factsheets
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EC number: 845-727-1 | CAS number: 1919868-77-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Administrative data
First-aid measures
General advice: Take off all contaminated clothing immediately.
If inhaled: Remove to fresh air. If symptoms persist, call a physician.
In case of skin contact: After contact with skin, wash immediately with plenty of soap and water. If skin reactions occur, contact a physician.
In case of eye contact: In the case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
If swallowed: If swallowed, seek medical advice immediately and show this container or label.
:
Fire-fighting measures
Suitable extinguishing media: Any
Specific hazards during fire-fighting: Fire may cause evolution of: Carbon monoxide (CO);Carbon dioxide (CO2);Nitrogen oxides (NOx);bromide of hydrogen
Special protective equipment for firefighters: In the event of fire, wear self-contained breathing apparatus.
Further information: Prevent fire extinguishing water from contaminating surface water or the ground water system.
Accidental release measures
Personal precautions: Use personal protective equipment. Avoid dust formation.
Environmental precautions: Do not flush into surface water or sanitary sewer system.
Methods for cleaning up: Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations
Handling and storage
Advice on safe handling: Avoid dust formation. Use with local exhaust ventilation. Avoid contact with skin, eyes and clothing.
Advice on protection against fire and explosion: Keep away from open flames, hot surfaces and sources of ignition.
Requirements for storage areas and containers: For storage suitable stores with adequate product-reception volume must be used. During handling local official regulations must be observed in order to avert impairment of water by the product.
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- 2811
Shipping information
- Proper shipping name and description:
- TOXIC SOLID, ORGANIC, N.O.S.
((R)-2-(2,5-DIFLUOROPHENYL)PYRROLIDINE (R)-2-HYDROXYSUCCINATE) - Chemical name:
- (R)-2-(2,5-DIFLUOROPHENYL)PYRROLIDINE (R)-2-HYDROXYSUCCINATE
- Language:
- English
- Class or division:
- Class 6: Toxic and infectious substances; Division 6.1
- Subsidiary hazard(s):
- Class 6: Toxic and infectious substances; Division 6.1
- Packing group:
- Packing group II: Substances presenting medium danger
- Labels:
- 6.1
SpecialProvisionsopen allclose all
Inland waterway transport (UN RTDG/ADN(R))
- UN number:
- 2811
Shippingopen allclose all
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
- UN number:
- 2811
Shipping information
- Proper shipping name and description:
- TOXIC SOLID, ORGANIC, N.O.S.
((R)-2-(2,5-DIFLUOROPHENYL)PYRROLIDINE (R)-2-HYDROXYSUCCINATE) - Chemical name:
- (R)-2-(2,5-DIFLUOROPHENYL)PYRROLIDINE (R)-2-HYDROXYSUCCINATE
- Language:
- English
- Class or division:
- Class 6: Toxic and infectious substances; Division 6.1
- Subsidiary hazard(s):
- Class 6: Toxic and infectious substances; Division 6.1
- Packing group:
- Packing group II: Substances presenting medium danger
- Labels:
- 6.1
Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
- UN number:
- 2811
Shipping information
- Proper shipping name and description:
- TOXIC SOLID, ORGANIC, N.O.S.
((R)-2-(2,5-DIFLUOROPHENYL)PYRROLIDINE (R)-2-HYDROXYSUCCINATE) - Chemical name:
- (R)-2-(2,5-DIFLUOROPHENYL)PYRROLIDINE (R)-2-HYDROXYSUCCINATE
- Language:
- English
- Class or division:
- Class 6: Toxic and infectious substances; Division 6.1
- Subsidiary hazard(s):
- Class 6: Toxic and infectious substances; Division 6.1
- Packing group:
- Packing group II: Substances presenting medium danger
- Labels:
- 6.1
Remarksopen allclose all
SpecialProvisionsopen allclose all
Exposure controls / personal protection
This substance is handled under Strictly Controlled Conditions in accordance with REACH regulation Article 17(3) for on-site isolated intermediates and, in case the substance is transported to other sites for further processing, the substance should be handled at these sites under the Strictly Controlled Conditions as specified in REACH regulation Article 18(4). Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management systems is available at each manufacturing site.
Stability and reactivity
Hazardous decomposition products: Carbon monoxide (CO) Carbon dioxide (CO2) Nitrogen oxides (NOx) bromide of hydrogen
deflagration ability: ca. 60 °C Method: VDI 2263-1, Non-deflagrating
Disposal considerations
During the whole life cycle of the substance all necessary measures in accordance to art. 18(4) of (EC) 1907/2006 are undertaken. The substance is handled under strictly controlled conditions.
Dispose in accordance with current regulations and, if necessary, after consultation with the site operator and/or with the responsible authority, the product may be taken to a waste disposal site or incineration plant.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.