Registration Dossier
Registration Dossier
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EC number: 906-089-0 | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
In a 48 h acute toxicity study conducted according to OECD guideline 202 and in compliance with GLP, water fleas (Daphnia magna) were exposed to the test substance under semi-static conditions at WSFs individually prepared at loading rates of 2.2, 4.6, 10, 22, 46 and 100 mg/L. Test solutions were renewed after 24 hours. Exposure concentrations were verified by a validated method: in the freshly prepared WSFs, the measured concentrations were at t=0 7 between 1.72 and 8.2 mg/L and these concentrations remained stable during the renewal periods, i.e. 81-105% of the initial concentrations. Effect parameters were based on average exposure concentrations, calculated to be respectively 1.7, 2.3, 4.6, 6.8, 7.4 and 7.3 mg/L. The 48h-EC50 was 5.1 mg/L (95% CI 4.3 - 5.8 mg/L). The study is considered to be reliable without restrictions.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Dose descriptor:
- EC50
- Effect concentration:
- 5.1 mg/L
Additional information
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