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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2020
Report date:
2020

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7950 (Vapor Pressure)
Deviations:
no
GLP compliance:
yes
Type of method:
effusion method: isothermal thermogravimetry

Test material

Constituent 1
Chemical structure
Reference substance name:
(2S)-1,1-bis(4-fluorophenyl)propan-2-yl L-alaninate hydrochloride
Cas Number:
2171323-89-8
Molecular formula:
C18H20CIF2NO2
IUPAC Name:
(2S)-1,1-bis(4-fluorophenyl)propan-2-yl L-alaninate hydrochloride
Specific details on test material used for the study:
Substance name: BFPA HCl salt
Lot #: SS17000577 (TSN400390)
Purity: 100%

Results and discussion

Vapour pressureopen allclose all
Key result
Test no.:
#1
Temp.:
20 °C
Vapour pressure:
0 Pa
Remarks on result:
other: 6e-7 mm Hg
Key result
Test no.:
#1
Temp.:
25 °C
Vapour pressure:
0 Pa
Remarks on result:
other: 1e-6 mm Hg

Applicant's summary and conclusion

Conclusions:
The vapour pressure of the test substance was determined to be 8E-5 Pa (6E-7 mm Hg) at 20°C and 2E-4 Pa (1E-6 mm Hg) at 25°C.
Executive summary:

The vapour pressure was determined according to the regulatory guidelines EC Method A.4, OPPTS 830.7950 and OECD 104 by the effusion method using isothermal thermogravimetry analysis.


The vapour pressure of the test substance was determined to be 8E-5 Pa (6E-7 mm Hg) at 20°C and 2E-4 Pa (1E-6 mm Hg) at 25°C.