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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
hydrolysis
Type of information:
experimental study
Adequacy of study:
key study
Study period:
02.-11.06.1997
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1997
Report date:
1997

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: 92/69/EWG, C.7 (Hydrolyse); OECD 111
GLP compliance:
yes (incl. QA statement)

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
PD 132408
Lot number 704010
Purity: 99.5 %
Radiolabelling:
no

Study design

Buffers:
ph 4
pH 7
pH 9

Results and discussion

Dissipation DT50 of parent compoundopen allclose all
pH:
4
Temp.:
25 °C
Hydrolysis rate constant:
s-1
DT50:
4 896 h
pH:
7
Temp.:
25 °C
Hydrolysis rate constant:
s-1
DT50:
3 936 h
pH:
9
Temp.:
25 °C
Hydrolysis rate constant:
s-1
DT50:
792 h

Any other information on results incl. tables

According to the test method it can be estimated that:

50 % hydrolysis occuring in 2.4 h at 50°C is equivalent to a half-life of 1 day at 25°C.

10 % hydrolysis occuring in 5 days at 50°C is equivalent to a hlaf-life of 1 year at 25°C.

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
The half-life at 25°C can be estimated as being between 1 day and 1 year at pH 4,7 and 9.