Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 300-344-4 | CAS number: 93925-42-9
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
see discussion
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 0.839 ng/L
Additional information
Read-across between dibutyltin compounds to to dibutyl diacetate concerning aquatic toxicity endpoints was considered appropriate as dibutyltin and octyltins are known to hydrolyse rapidly in water (as presented by Yoder 2003, under the data requirement hydrolysis), and form, in the case of dibutyltins, dibutyltin oxide.
The key study, Steger-Hartmann and Wendt (1998) has been allocated a Klimisch score of 2, as it was used as read across from a supporting substance. The study was performed to the guideline OECD 203. Only one fish died during the course of the 72 hour study, when tested up to the saturation point. Only a 72 hour LOEC of 3.1 mg/L could be determined from the study.
The Nagase et al (1991) study (the data were sourced from the same publication but reported as two separate endpoints, results from tests with dibutyltin di(acetate) and dibutyltin oxide respectively) have been allocated a Klimisch score of 4 due to a lack of detail in the reporting of the methods and results. Only 48 hours LC50's were reported. These studies are considered to be supporting studies.The 48 hr LC50 for di-n-butyltin diacetate was determined to be 1.07 x 10 -2 mmol dm-3 in the red killifish under semi-static conditions. For DBTO, the short term LC50 was 0.839 mg/L.
Tests in microorganism, algae and daphnia magna showed an different behavior and different effects in environment as the pure dibutyltin compound. In conculsion this endpoints are not applicable. In due to animal protection no new testing
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
