Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
Not Known
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Data obtained from an authoritative secondary source
Cross-reference
Reason / purpose for cross-reference:
reference to other study

Data source

Reference
Reference Type:
review article or handbook
Title:
Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold, p. 193
Author:
Lewis, R.J
Year:
1996
Bibliographic source:
http://toxnet.nlm.nih.gov/cgi-bin/sis/search

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
No other information from the data source
GLP compliance:
not specified
Remarks:
No other information from the data source

Test material

Constituent 1
Chemical structure
Reference substance name:
2-pyridylamine
EC Number:
207-988-4
EC Name:
2-pyridylamine
Cas Number:
504-29-0
Molecular formula:
C5H6N2
IUPAC Name:
pyridin-2-amine

Administration / exposure

Route of administration:
intraperitoneal

Results and discussion

Effect levels
Dose descriptor:
LD50
Effect level:
23 other: mg/kg

Any other information on results incl. tables

No other information from the data source

Applicant's summary and conclusion

Conclusions:
The LD50 of mouse is found to be 23 mg/kg through intraperitonial administration of 2-Aminopyridine
Executive summary:

The LD50 of mouse is found to be 23 mg/kg through intraperitonial administration of 2-Aminopyridine