Registration Dossier
Registration Dossier
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EC number: 247-988-1 | CAS number: 26762-93-6
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The toxicity of diisopropylbenzene hydroperoxide to microorganisms was estimated in a test according to the OECD guideline 209. EC50 and EC10 were determined to be respectively 46.7 mg/L and 10.6 mg/L active ingredient for total respiration.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 46.7 mg/L
- EC10 or NOEC for microorganisms:
- 10.6 mg/L
Additional information
The toxicity of diisopropylbenzene hydroperoxide to microorganism was estimated in a test according to the OECD guideline 209 “Activated Sludge, Respiration Inhibition Test” and GLP requirements (Gancet, 2013).The effect is assessed by measuring the micro-organisms respiration rates on a sample of activated sludge during an incubation period of 3 hours.Three respiration rates were evaluated : total respiration rate, heterotrophic respiration rate and nitrification respiration rate by difference between total and heterotrophic respiration rates.
EC50 of the reference item 3,5 -dichlorophenol was 15 mg/L, between 2 and 25 mg/L for total respiration; 23 mg/L, between 5 and 40 mg/l for heterotrophic respiration, but could not be determined for nitrification respiration.
EC50 and EC10 for the test item was determined to be respectively 79 mg/L and 18 mg/L for total respiration corresponding to 46.7 and 10.6 mg/L active ingredient.
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