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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Summary only

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1990

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 401 (Acute Oral Toxicity)
Deviations:
not specified
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
(2-{2-[(3-aminophenyl)formamido]ethanesulfonyl}ethoxy)sulfonic acid
EC Number:
601-770-6
Cas Number:
121315-20-6
Molecular formula:
C11H16N2O7S2
IUPAC Name:
(2-{2-[(3-aminophenyl)formamido]ethanesulfonyl}ethoxy)sulfonic acid
Details on test material:
FAT 92274/A

Test animals

Species:
other: young adult albino rat
Sex:
male/female

Administration / exposure

No. of animals per sex per dose:
female 3
male 3

Results and discussion

Any other information on results incl. tables

ALD50 to male rats:> 2000 mg/kg mg/kg body weight

ALD50 to female rats:> 2000 mg/kg mg/kg body weight

ALD50 to both sexes: > 2000 mg/kg mg/kg body weight > 2000 mg/kg mg/kg body weight

Remarks: Piloerection, hunched posture, and dyspnea were seen, being common symptoms in acute toxicity testing. Additionally, diarrhea was noticed in the males. The animals recovered within 5 to 6 days. At autopsy, no deviations from normal morphology were found.

Applicant's summary and conclusion

Interpretation of results:
practically nontoxic
Remarks:
Migrated information
Conclusions:
not classifed
Executive summary:

not classifed