Registration Dossier
Registration Dossier
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EC number: 269-125-8 | CAS number: 68187-80-4
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Based on a good quality and reliable OECD guideline study conducted with the read across substance amides, C18(unsatd.), N,N-bis(hydroxyethyl), the 96-h LC50 and NOEC were calculated to be 5.1 and 1.25 mg/L respectively. Based on read-across these values will be used for the assessment of HE Rape Oil, reaction product with diethanolamine.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 5.1 mg/L
Additional information
A study was conducted to evaluate the acute toxicity of the read across substance amides, C18(unsatd.), N,N-bis(hydroxyethyl) to Danio rerio (Zebrafish) under static conditions according to OECD guideline 203. In this study, the nominal test substance concentrations were as follows: 0, 0.625, 1.25, 2.50, 5.00 and 10.0 mg/L. Seven test organisms in single replicates were exposed to each test concentration and control (i.e., dilution water). Mortality was observed at 24, 48, 72 and 96 h interval. Under the test conditions, the 96-h LC50 and NOEC of the test substance were calculated to be 5.1 mg/L and 1.25 mg/L respectively. The test substance was found to be toxic to zebra fish after 96 h at concentration levels of 2.5 mg/L and higher (Scheerbaum, 2002).
Based on read-across these values will be used for the assessment of HE Rape Oil, reaction product with diethanolamine.
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