Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 269-125-8 | CAS number: 68187-80-4
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Based on a guideline compliant study conducted with nominal concentrations of the structurally similar amides, C16-18 (even-numbered) and C18-unsatd., N,N-bis(hydroxyethyl) in Scenedesmus subspicatus, the 24 -72 h ErC50 was determined to be 18.6 mg/L. Further, the 72 h EbC50 was 23.4 mg/L and the NOEC was 2.0 mg/L. Based on read-across these values will be used for the assessment of HE Rape Oil, reaction product with diethanolamine.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 18.6 mg/L
- EC10 or NOEC for freshwater algae:
- 1.4 mg/L
Additional information
A study was conducted to determine the toxicity of the structurally similar amides, C16-18 (even-numbered) and C18-unsatd., N,N-bis(hydroxyethyl) to the green algae Scenedesmus subspicatus according to EU Method C.3. Algae were exposed to the test substance for 72 h at 0, 0.5, 1.0, 2.0, 4.0, 8.0, 16.0 and 32.0 mg/L in a static system. Biomass and growth rate were determined. Under the conditions of the study, the 24 -72 h ErC50 of the test substance for Scenedesmus subspicatus, based on nominal concentrations, was 18.6 mg/L. The 72 h EbC50 was 23.4 mg/L and the NOEC was 2.0 mg/L (Scholz, 1991).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
