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Registration Dossier
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EC number: 261-879-6 | CAS number: 59719-67-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.019 mg/L
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 0.186 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.002 mg/L
- Assessment factor:
- 10 000
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 89.4 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 0.709 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.071 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.131 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
PNEC freshwater sediment:
K_(susp-water) = 9.54
RHO_(susp) = 1150
PNEC_freshwater sediment = (K_(susp-water) / RHO_(susp)) * PNEC_water * 1000
= (9.54 / 1150) * 0.0186 * 1000
= 0.154 mg/kg wwt * 4.6
= 0.709 mg/kg dwt
PNEC marine water sediment:
K_(susp-water) = 9.54
RHO_(susp) = 1150
PNEC_marine water sediment = (K_(susp-water) / RHO_(susp)) * PNEC_marine water * 1000
= (9.54 / 1150) * 0.00186 * 1000
= 0.0154 mg/kg wwt * 4.6
= 0.0709 mg/kg dwt
PNEC soil:
K_(soil-water) = 10.6
RHO_(soil) = 1700
PNEC_soil = (K_(soil-water) / RHO_(soil)) * PNEC_water * 1000
= (10.6 / 1700) * 0.0186 * 1000
= 0.116 mg/kg wwt * 1.13
= 0.131 mg/kg dwt
Conclusion on classification
Acute aquatic toxicity:
Algae were the most sensitive species in acute aquatic toxicity tests with Incozol 4, resulting in a 72-hour EC50 of 18.6 mg/L. Based on acute aquatic toxicity results obtained, the test substance was not classified and labelled according to Regulation 1272/2008/EC (CLP), as amended for the tenth time in Regulation (EU) No 2017/776, with respect to short-term (acute) aquatic toxicity.
Chronic aquatic toxicity:
Incozol 4 was tested in an aquatic toxicity test with algae, according EU-method C.3 and OECD guideline 201. The 72-hour EC50 for growth rate was 18.6 mg/L and the 72-hour NOEC 0.0259 mg/L. The EC10 was calculated to be 0.194 mg/L. Due to the big diffenrence between EC50 and NOEC value the classification and labelling is based on the more reliable EC10 value. The test substance was shown to be not ready biodegradable. Thus, the substance has to be classiffied as long-term (chronic) aquatic toxic substance in cat. 2 (H411) according to Regulation (EC) No 1272/2008 (CLP), as amended for the tenth time in Regulation (EU) No 2017/776.
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