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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1989
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Data from WHO report on chlorophenols (collective views of an international group of experts)

Data source

Referenceopen allclose all

Reference Type:
review article or handbook
Title:
Chlorophenols other than pentachlorphenol (environmental health criteria 93)
Author:
EHC
Year:
1989
Bibliographic source:
http://www.inchem.org
Reference Type:
secondary source
Title:
Unnamed
Year:
1983

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 401 (Acute Oral Toxicity)
Deviations:
not specified
GLP compliance:
not specified
Test type:
standard acute method
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
4-chlorophenol
EC Number:
203-402-6
EC Name:
4-chlorophenol
Cas Number:
106-48-9
Molecular formula:
C6H5ClO
IUPAC Name:
4-chlorophenol

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
not specified
Control animals:
no

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
261 mg/kg bw
Based on:
test mat.

Applicant's summary and conclusion