Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 700-725-9 | CAS number: -
Sensitisation data (human)
Administrative data
- Endpoint:
- sensitisation data (humans)
- Type of information:
- experimental study
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Only secondary literature (review)
Data source
Reference
- Reference Type:
- publication
- Title:
- Final report on the safety assessment of candelilla wax, carnauba wax, japan wax and beeswax
- Author:
- Anonymus
- Year:
- 1 984
- Bibliographic source:
- Journal of the American College of Toxicology, 3 (3), 1-41
- Report date:
- 1984
Materials and methods
- Type of sensitisation studied:
- skin
- Study type:
- study with volunteers
- Principles of method if other than guideline:
- Summarised results from repeated insult patch test and from photosensitisation test
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Carnauba wax
- EC Number:
- 232-399-4
- EC Name:
- Carnauba wax
- Cas Number:
- 8015-86-9
- IUPAC Name:
- Carnauba wax
- Details on test material:
- RIPT: lipstick formulation containing 5.61% carnauba wax
Photosensitisation test: 25% carnauba wax dissolved in heavy mineral oil
Constituent 1
Method
- Type of population:
- general
- Subjects:
- RIPT: 151 men and women
Photosensitisation test: 23 individuals - Route of administration:
- dermal
Results and discussion
- Results of examinations:
- In RIPT the test item neither showed sensitising nor clinically significant skin irritating properties
The test item was not phototoxic or photosensitising.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
