Registration Dossier
Registration Dossier
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EC number: 411-380-6 | CAS number: 147315-50-2 CG 30-1577
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: OECD method, GLP compliance
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 2 012
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: OECD GUIDELINE 401 (84/449/EEC B.1)
- GLP compliance:
- yes
- Test type:
- standard acute method
Test material
- Reference substance name:
- 2-(4,6-diphenyl-1,3,5-triazin-2-yl)-5-((hexyl)oxy)phenol
- EC Number:
- 411-380-6
- EC Name:
- 2-(4,6-diphenyl-1,3,5-triazin-2-yl)-5-((hexyl)oxy)phenol
- Cas Number:
- 147315-50-2
- Molecular formula:
- C27H27N3O2
- IUPAC Name:
- 2-(4,6-diphenyl-1,3,5-triazin-2-yl)-5-(hexyloxy)phenol
Constituent 1
Test animals
- Species:
- rat
Administration / exposure
- Vehicle:
- other: 0.5% /w/w) CMC in0.1% aqueous polysorbate 80
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Mortality:
- Male: 2000 mg/kg bw; Number of animals:5; Number of death:0
Female: 2000 mg/kg bw; Number of animals:5; Number of death:0 - Clinical signs:
- other: Signs of toxicity related to dose levels: COMMON SYMPTOMS IN ACUTE TESTS, (PILOERECTION, HUNCHED, POSTURE, EXOPHTALMOS, DYSPNEA). THE ANIMALS RECOVERED WITHIN 6-7 DAYS. ADDITIONALLY, REDUCED LOCOMOTOR ACTIVITY WAS OBSERVED IN ALL ANIMALS.
- Gross pathology:
- Effects on organs:
NONE
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
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