Registration Dossier
Registration Dossier
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EC number: 485-140-4 | CAS number: 515815-48-2
Guidance on Safe Use
Administrative data
First-aid measures
General advice : Remove affected person from danger area. Do not leave affected persons unsupervised. Seek medical treatment. First aid personnel should pay attention to their own safety.
Eye contact : Rinse opened eye for several minutes under running water. Protect unharmed eye.
Skin contact : Wash off immediately with plenty of water. Take off immediately all contaminated clothes.
Inhalation : Supply fresh air or oxygen; call for doctor.
Ingestion : Rinse mouth immediately and then drink plenty of water, seek medical attention.
Notes to physician
Symptoms : lowered blood pressure, diarrhea, vomiting, headache
Treatment : Medical monitoring for at least 24 hours.
Fire-fighting measures
Suitable extinguishing media : Use extinguishing measures to suit surroundings., water, foam, carbon dioxide, dry extinguishing media
Hazards during fire-fighting: Can be released in case of fire: nitrogen oxides, Hydrogen chloride gas, carbon oxides
Protective equipment for fire-fighting: In case of fire and/or explosion do not breathe fumes. Self-contained breathing apparatus.
Further information: Dispose of fire debris and contaminated extinguishing water in accordance with official regulations.
Accidental release measures
Personal precautions: Wear protective equipment. Keep unprotected persons away. Avoid dust formation.
Environmental precautions: Do not discharge into drains/surface waters/groundwater.
Methods for cleaning-up or taking-up: For large amounts: Dampen, pick up mechanically and dispose of. For residues: Pack in tightly closed containers for disposal. Cleaning operations should be carried out only while wearing breathing apparatus. Avoid raising dust.
Handling and storage
BIBR 277 CL is handled under Strictly Controlled Conditions in accordance with REACH regulation Article 17(3) for on-site isolated intermediates and, in case the substance is transported to other sites for further processing, the substance should be handled at these sites under the Strictly Controlled Conditions as specified in REACH regulation Article 18(4). Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management systems is available at each manufacturing site.
BIBR 277 CL is handled under Strictly Controlled Conditions as defined under REACH Article 18(4) throughout its life cycle.
Specifically the substance is rigorously contained by technical means during its whole lifecycle; procedural and control technologies are used to minimise emissions and any resulting exposures; only properly trained and authorised personnel handle the substance; special procedures such as purging and washing are applied during cleaning and maintenance works, in cases of accident and where waste is generated, proceduraland/or control technologies are used to minimise emissions and the resulting exposures; and substance-handling procedures are well documented and strictly supervised by the site operator.
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- 3077
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Marine transport (UN RTDG/IMDG)
- UN number:
- 3077
Shipping information
- Proper shipping name and description:
- ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
(4'-(1,7'-Dimethyl-2'-propyl-1H-(2,5')bibenzoimidazolyl-3'-ylmeth yl)-biphenyl-2-carboxylic acid Hydrochloride) - Chemical name:
- ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
(4'-(1,7'-Dimethyl-2'-propyl-1H-(2,5')bibenzoimidazolyl-3'-ylmeth yl)-biphenyl-2-carboxylic acid Hydrochloride)
- Marine pollutant
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Air transport (UN RTDG/ICAO/IATA)
- UN number:
- 3077
Shipping information
- Proper shipping name and description:
- ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
(4'-(1,7'-Dimethyl-2'-propyl-1H-(2,5')bibenzoimidazolyl-3'-ylmeth yl)-biphenyl-2-carboxylic acid Hydrochloride) - Chemical name:
- ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
(4'-(1,7'-Dimethyl-2'-propyl-1H-(2,5')bibenzoimidazolyl-3'-ylmeth yl)-biphenyl-2-carboxylic acid Hydrochloride)
- Labels:
- Environmentally Hazardous
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Exposure controls / personal protection
BIBR 277 CL is handled under Strictly Controlled Conditions in accordance with REACH regulation Article 17(3) for on-site isolated intermediates and, in case the substance is transported to other sites for further processing, the substance should be handled at these sites under the Strictly Controlled Conditions as specified in REACH regulation Article 18(4). Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management systems is available at each manufacturing site.
BIBR 277 CL is handled under Strictly Controlled Conditions as defined under REACH Article 18(4) throughout its life cycle.
Specifically the substance is rigorously contained by technical means during its whole lifecycle; procedural and control technologies are used to minimise emissions and any resulting exposures; only properly trained and authorised personnel handle the substance; special procedures such as purging and washing are applied during cleaning and maintenance works, in cases of accident and where waste is generated, proceduraland/or control technologies are used to minimise emissions and the resulting exposures; and substance-handling procedures are well documented and strictly supervised by the site operator.
Stability and reactivity
Maximum handling temperature for safety reasons (TmaxSi) : when a venting system is used approx. 140 °C 24 hrs.
Hazardous reactions: Dust can form an explosive mixture with air.
Disposal considerations
Dispose of in accordance with local authority regulations
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
