Registration Dossier
Registration Dossier
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EC number: 220-860-2 | CAS number: 2920-38-9
Endpoint summary
Administrative data
Description of key information
The LD50 for acute dermal toxicity in rats is greater than 2000 mg/kg bw (OECD 423, GLP) (BASF 2012). No adverse effects were observed.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Quality of whole database:
- valid without restriction
Additional information
Reliable data is available for acute dermal toxicity in rats (OECD 402, GLP) (BASF 2012). No indication of toxicity (local or systemic) was observed in the male and female rats that had been given a single dermal dose of 1000 or 2000 mg/kg bw.
Based on the physico-chemical properties, the substance is expected to permeate the skin easily. It is used as an intermediate in industrial settings. Therefore, the dermal route of exposure is considered to be the most relevant route.
Justification for selection of acute toxicity – dermal endpoint
only study available
Justification for classification or non-classification
Dangerous Substance Directive (67/548/EEC)
There is reliable and valid experimental data available for the acute dermal toxicity of the test substance. As a result the substance is considered to be not classified for acute dermal toxicity under Directive 67/548/EEC.
Classification, Labeling, and Packaging Regulation (EC) No. 1272/2008
There is reliable and valid experimental data available for the acute dermal toxicity of the test substance. As a result the substance is considered to be not classified for acute dermal toxicity under Regulation (EC) No.1272/2008, as amended for the third time in Directive EC 618/2012.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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