Registration Dossier
Registration Dossier
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EC number: 937-559-3 | CAS number: 1360085-10-4
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Title:
- Unnamed
- Year:
- 1 995
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 401 (Acute Oral Toxicity)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- sodium 7-[(ethoxycarbonyl)amino]-4-hydroxynaphthalene-2-sulfonate
- EC Number:
- 937-559-3
- Cas Number:
- 1360085-10-4
- Molecular formula:
- C13H12NNaO6S
- IUPAC Name:
- sodium 7-[(ethoxycarbonyl)amino]-4-hydroxynaphthalene-2-sulfonate
- Details on test material:
- 85.23% active ingredient
Constituent 1
Test animals
- Species:
- rat
- Strain:
- other: Hanlbm: WIST (SPF)
- Sex:
- male/female
Results and discussion
Effect levels
- Sex:
- male/female
- Effect level:
- >= 2 000 mg/kg bw
Any other information on results incl. tables
The test substance was administered to groups of 5 male and 5 female rats by oral gavage, at single dose of 2000 mg test article/kg body weight.
There were no deaths as a result of treatment with the test article.
No clinical signs of toxicity were observed during the observation period.
There was no effect on body weight gain during the observation period.
No organ abnormalities were observed at necropsy.
Applicant's summary and conclusion
- Interpretation of results:
- practically nontoxic
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- CONCLUSION
The mean lethal dose of tested substance after single oral administration to rats of both sexes, observed
over a period of 14 days, could not be estimated, because LD50 : greater than 2000 mg/kg - Executive summary:
LD50 : greater than 2000 mg/kg
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