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Long-term toxicity to aquatic invertebrates

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Description of key information

The seven day inhibition concentration (IC25) was determined to be 0.648 mg/l, and the 7-day reproductive NOEC and LOEC value were determined to be 0.6 and 1.0 mg/l, respectively. The 7-day survival NOEC and LOEC values were also determined to be 0.6 and 1.0 mg/l, respectively.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
0.6 mg/L

Additional information

A study was performed to determine the seven-day survival LOEC (lowest observed effect concentration) and NOEC (no observed effect concentration), and the three-brood IC25, LOEC (lowest observed effect concentration) and NOEC (no observed effect concentration) of the test item, PR-9026 Acetate Salt, to Ceriodaphnia dubio reproduction under chronic, static-renewal test conditions.

The study was conducted according to Annual Book of ASTM Standards, Volume 11.05, Biological Effects and Environmental Fate; Biotechnology; Pesticides, ASTM E1295, 1999.

Test concentrations were: 0 (dilution water control), 0.130, 0.216, 0.360, 0.600 and 1.00 mg/L

The seven day inhibition concentration (IC25) was determined to be 0.648 mg/l, and the 7-day reproductive NOEC and LOEC value were determined to be 0.6 and 1.0 mg/l, respectively. The 7-day survival NOEC and LOEC values were also determined to be 0.6 and 1.0 mg/l, respectively.

Control organisms produced acceptable broods and supported acceptable survival.

All water chemistry values were within recommended thresholds.