Registration Dossier
Registration Dossier
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EC number: 940-679-9 | CAS number: -
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
No data on acute and chronic toxicity to aquatic algae are available for H250 sulphonic acid. Data from LABS Na (CAS no: 68411-30-3) as structural analogue was used to understand the acute and chronic toxicity profile of substance to algae. The 72-hr EbC50 was 47.3 mg/L, and the 72-hr ErC50 was 127.9 mg/L for algae. The 72-hr NOEC for algae was 2.4 mg/L.
Key value for chemical safety assessment
Additional information
Benzenesulphonic acid, dimethyl-,mono C14-16-alkyl derivative (H250 sulphonic acid) is a UVCB. Based on structural and functional similarities, data on Benzenesulphonic acid, 4-C10-13-sec-alkyl derivatives (LABS; CAS no: 85536-14-7) being registered under REACH, LABS Na (CAS no: 68411-30-3) being registered under REACH and LAB (CAS no: 67774-74-7) being registered under REACH are suitable as supporting study in case where specific data on the substance is lacking.
To assess the acute toxicity profile of the substance to aquatic algae, structural analogue approach was used from LABS Na (CAS no: 68411-30 -3). The acute toxicity to algae of LABS Na was determined in 88/302/EWG guideline study.This study examined the potential of the test substance to cause toxicity to aquatic algae. Scenedesmus subspicatus was exposed to concentrations of 0, 0.6, 2.4, 10, 40, or 160 mg/L of test substance for 72 hrs. The cell concentration was measured at 24, 48, and 72 hrs. The 72-hr NOEC for algae was 2.4 mg/L. The 72-hr EbC50 was 47.3 mg/L, and the 72-hr ErC50 was 127.9 mg/L for algae.
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