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EC number: 473-450-2 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
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- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 27 February 2006 - 25 April 2006
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: This study has been performed according to OECD and EC guidelines and according to GLP principles.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 006
- Report date:
- 2006
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- column elution method
Test material
- Reference substance name:
- No.338 RED
- IUPAC Name:
- No.338 RED
- Details on test material:
- Description: red powder
Batch number: 50670
Constituent 1
Results and discussion
Water solubility
- Water solubility:
- < 0 g/L
- Temp.:
- 20 °C
- pH:
- > 6.3 - < 7
Any other information on results incl. tables
Preliminary test:
Since the test substance was of a very fine particle size, not all undissolved test substance was removed by centrifugation, and therefore the sample was also filtrated. However, also with filtration not all undissolved test substance was removed (determined using the Tyndall effect), so the determined water solubility during the preliminary test (7.93 x 10E-4 g/l; only Component 2 was detected in the sample solution) was an overestimation.
Main study:
Validation:
The linearity of the detector with respect to concentration was assessed over the nominal contrentration range of 0 to 25.0 mg/l. This was satisfactory with a correlation coefficient of >= 0.997 being obtained when assessing the three major components present in the test material on an individual basis.
Recovery of analysis of the sample procedure was assessed and proved adequate for the test (mean recovery 80.4 -90.4% for 0.25 mg/l nominal concentration and 74.0 -96.2% for 0.10 mg/l nominal concentration).
Concentrations have not been corrected for recovery of analysis.
Samples:
Overall, for all components and for both flow rates, the water solubility was determined to be < 1.0 x 10E-4 g/l at 20.0 +/-0.5°C (pH 6.3 -7.0). The incomplete removal of all excess, un-dissolved test material by the filtration step applied to the sample clean up was confirmed to have no significant impact on the test. This was since any remaining contamination of the sample solutions still resulted in a concentration below that for which the recovery procedure had been succesfully validated, the nominal concentration subsequently used as the reported limit value of solubility.
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information): insoluble (< 0.1 mg/L)
The water solubility of the test substance was determined to be < 1.0 x 10E-4 g/l at 20.0 +/-0.5°C (pH 6.3 -7.0), monitoring the three significant components of the test material.
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