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EC number: 221-904-3 | CAS number: 3275-24-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 17.06. to 15.07.1998
- Reliability:
- 1 (reliable without restriction)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I))
- Deviations:
- no
- GLP compliance:
- yes
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, non-adapted
- Details on inoculum:
- From 10 areas: Fushiko River disposal site (Sapporo, Hokkaido), Kashima disposal site (Kashima, Ibaragi), Nakahama disposal site (Osaka), Ochiai disposal site (Shinjyuku, Tokyo), Kitagami River (Ishimaki, Miyagi), Shinano River (Nishi Kanbara, Niigata), Yoshino river (Tokushima), Lake Biwa (Otsu, Shiga), Hiroshima Bay (Hiroshima), Doukai Bay (Kita Kyusyu, Fukuoka)
Collected in March 1998
How to collect (1) sewage: returned sludge at disposal site (2) river, lake, sea: top soil at the water’s edge, which has exposure to air and surface water
mixture of new and old sludge: mixed filtrate 5 L of mixed sludge liquid collected from above mentioned areas and filtrate 5 L of active sludge (2), which was cultured 3 months, and then adjusted pH 7.0+-1.0 and aerated (3) in a fermenter
(2) active sludge, which is 10L mixed sludge liquid corrected from above mentioned areas cultured according to 11.4.
(3) out door air through pre-filter was used for aeration.
Cultivation: after aeration in the fermenter was stopped for around 30 min., 1/3 of clear supernatant liquid was removed. Then, added same volume of dechlorinated water, aerated again, and added synthesized sewage (4) to have concentration of clear supernatant liquid at 0.1%. Repeated this operation once a day to cultivate and to reach active sludge. Temperaturen for cultivation was set at 25℃ +- 2℃
(4) dissolved glucose, peptone, calcium dihydrogen phosphate into the synthesized sewage, so that each reaches 4 (W/V) % and adjusted pH 7.1+-1.0 by using sodium hydroxide - Duration of test (contact time):
- 28 d
- Initial conc.:
- 100 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- 3 vessels with sludge and test substance: 100 mg/l test substance; 30 mg/l activated sludge, the Ph value was adjusted from ca 10 to ca 7 with sodium hydroxide
1 vessel with sludge and reference substance: 100 mg/l aniline; 30 mg/l activated sludge
1 vessel control blank
1 vessel water plus test substance
Tempereature: 25°C+-1°C - Reference substance:
- aniline
- Preliminary study:
- no
- Test performance:
- regular test under regular conditions
- Key result
- Parameter:
- % degradation (O2 consumption)
- Remarks:
- BOD
- Value:
- 88
- Sampling time:
- 28 d
- Remarks on result:
- other: readily biodegradable
- Key result
- Parameter:
- % degradation (test mat. analysis)
- Remarks:
- HPLC
- Value:
- 100
- Sampling time:
- 28 d
- Remarks on result:
- other: readily biodegradable
- Key result
- Parameter:
- % degradation (TOC removal)
- Value:
- 96
- Sampling time:
- 28 d
- Remarks on result:
- other: readily biodegradable
- Results with reference substance:
- BOD = 72.1 mg after 28 days
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Executive summary:
The test was carried out according to OECD 301 C (MITI) guideline under GLP conditions. The test results showed a biodegradation of 88% under the test conditions and the substance can be considered as readily biodegradable.
- Endpoint:
- biodegradation in water: ready biodegradability
- Data waiving:
- study technically not feasible
- Justification for data waiving:
- other:
- Justification for type of information:
- Titanium tetrakic(dimethylammonium) can only be handled air-free. It is a flammable liquid and very unstable (detailed description in chapter 1.2 or 5.2.1 or 13). Within seconds it reacts violently in contact with moisture or water. A biodegradation test in water is technically not feasible. The decomposition products are dimethylamine and titanium dioxide. Available data of dimethylamine show, this substance is readily biodegradable. Titanium dioxide is an inorganic substance and a biodegradation test is technically not feasible.
Dimethylamine is found quite widely distributed in animals and plants, and is present in many foods at the level of a few mg/kg.
Referenceopen allclose all
Description of key information
Titanium tetrakic(dimethylammonium) can only be handled air-free. It is a flammable liquid and very unstable (detailed description in chapter 1.2 or 5.2.1 or 13). Within seconds it reacts violently in contact with moisture or water. A biodegradation test in water is technically not feasible. The decomposition products are dimethylamine and titanium dioxide. Available data of dimethylamine show, this substance is readily biodegradable. Titanium dioxide is an inorganic substance and a biodegradation test is technically not feasible.
Dimethylamine is found quite widely distributed in animals and plants, and is present in many foods at the level of a few mg/kg.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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